Peptidases • Mucoromycotina
Annotations/GenomesAbscae1Absrep1Amyrou1Bacci1Benpoi1Blatri1Blatri_F921_1Blatri_F986_2Chabre1Chlpad1Chocucu1Cirumb1Cokrec1Cunech1Dicele1Dicrob1Ellano2Endsp1Fenlin1FenlinCB54_1Gilper1Gonbut1Halrad1Helpul1Hesve2finisherSCJimfl_AD_1Jimfl_GMNB39_1Jimlac1Kircor1Lenpar1Lenzyc1Liccor1Lichy1Mucci2Muccir1_3Mucend1Mucfus1Muclan1Mucmuc1Mucrac1Mycafr1Mycind1Parpar1Phaart1Phybl2PhyblU21_2Phybl_L51_1Phybla1Pilano1Pilumb1PnitS607_1PnitS608_1PnitS609_1Radspe1Rhich1Rhimi1_1Rhimi_ATCC11559_1Rhimi_ATCC52814_1Rhior3Sakvas1Spifus1Spoumb1Synrac1Thaele1Umbelo1Umbisa1Umbra1Umbsp_AD052_1Zycmex1Zyghet1TotalAnnotation Description
Merops
35234230242225225125425724231625832724731828830929322733732326426725827928328528230736724723930531130428025424423830125623322526532328427827427626124026727427726437625323823229023922925528329429027427227733430219,667
282630312018191817232423212224252311343124242221261314123619192625242222171625201615192428342931191630323219352020203313193220232422222324311,620Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
112Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
44310433344323333332233476544425634454264343245544345535434433444323344265Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1113Water nucleophile; water bound by two Asp
373534403026262628332728223427283220323426282730273127323630313235353027243131272326303129272728302825282731452930282827232431342524242434312,047Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
567655556656676771456644641211186544566555546756767856771058646455566222255415Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
121623234133222212231133213131122122122233433422221322122124332312154Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111111118Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile: catalytic residues in the order Cys, His in sequence
2121111111112212111111121112221111111111111111112111123221174Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
13221122112122121212112122212211121212211211121221211282Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
9911973546837757774666657547595587779788833766665764446127771354567666687448Families of peptidase inhibitors not assigned to clans
111115
111121131111111112111111129
111112111111111111121111127
1111116
11111211222133111221321131122222153
112
89101111131155
11
22211222122212113112211212111121111112111111122222112211311111190
231522222224113322442222211545332322222223411113311131111221142331344157
11111111111111111111111111111111111111111111111112111111111111164Families of metallopeptidases not assigned to clans
171719261823222219172817171419292314201817121319121720211911121616232123182023201512201617141615201917151717281815151817141815261615222018241,281Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
3132222217Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
13131113373311114112212249Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
3444444443444344434443343523442454454454444533334433338444433444333346265Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
12151315101110101212111191113121281414121011141110101012109911131313131310131213121212131313121213131312161411121391291112101011101212821Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
15171616977710148178131216111415168131210111616181599191711111089111299102015151413108131213101411111016611121410161617162412880Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1513511655579555987866678126876108467712887777777698787687855654456687129101256508Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111121111111211121111111111131111221111111111111111112111111121111277Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
57674444444545554255525536377573365344544455544555444410656645436342355324Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Water nucleophile; water bound by two cobalt ions ligated by Glu, Glu, His, His, Asp
1111116Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
1051322125222412422312233633321114223213211112211122111111112443331148Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
333332352018171819301725212118222413192016222320212324233621202020232416201719241921212117181818191918182019311719193220192320202019181924251,498Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
24443443323247123522323235531024353354552333333234345425322342224323324232Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
11111111121111111119Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
181217227151820619152891514141072523111091171216141211914151098141421108611191918201971116151515151188181591111111171081814935Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
898559965650514844754693608466776568938651746670807574729254477782676356474866564947618655575856574856565659704652485356505776677978717394694,548Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
11111113111133232211214311121211115212111121124178Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
6437444443353543445544364234543745456665547444447355447655243437333348308Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
3115Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
221212211112112121111111231212113411111221332221111111112111111122321102Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1113Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
695115124563551085619868549222866767643274674976675646659654486475454565389Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
2213111111121111111125Families of peptidases of unknown catalytic mechanism not assigned to clans
2112111112111111111111111123112111111111111111111111211111111111173
202120262222212021201921182528252513191720152019232120242418162023241717191522152519201926212020182023232327242420172317202123201817171421151,430
11
1112212131111111112126
11
1111116