Peptidases • Coccidioides immitis RS
Annotations/GenomesAspca3Aspni5Aspnid1Aspor1Cocim1Eurhe1Pench1TotalAnnotation Description
Merops
4092914142202442951,873
1741358956Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
4217Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
833647765Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
381034203133166Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
33323216Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
3231110Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11114Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile; active peptidase is a homodimer with active site His and Glu from one monomer and Cys from the other. Catalytic residues in the order His, Glu, Cys in each monomer.
112Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
6433420Water nucleophile; water bound by Gln and Glu; all endopeptidases
55446529Families of peptidase inhibitors not assigned to clans
11
11
11
11
1321310
4111310
671427339Families of metallopeptidases not assigned to clans
18162515121096Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
112217Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
112Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
115774943Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
244026121625143Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
14813681160Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
41133416Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
2114Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
325Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
231726192020125Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
114937842Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
21216Serine or threonine nucleophile; N-terminal nucleophile
1149196756Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
16661153617092603Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
617511030Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
21754524Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
22321212Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
32122111Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
39113Families of peptidases of unknown catalytic mechanism not assigned to clans
1111116
11
138197121069
11
11
112
3837351