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Peptidases • Phyllosticta citricarpa CBS 127454 v1.0
Annotations/GenomesAplpr1Botdo1_1Dipse1Macph1Neopa1Phcit1Phcitr1Phycit1Phycitr1Sacpr1TotalAnnotation Description
Merops
2943943054053632712642552652903,106
25262023201515151729205Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
21115Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
584955334652Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
22252622272523222326241Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
213222223322Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
211112321216Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111115Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
123Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11121118Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
322314523328Water nucleophile; water bound by Gln and Glu; all endopeptidases
534345455442Families of peptidase inhibitors not assigned to clans
1111127
12111118
11
562632222333Families of metallopeptidases not assigned to clans
925152518151212158154Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
222541111120Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
212312222219Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
536877667661Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
20221924281718181821205Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
101912171499101010120Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11114Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
333333333330Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
232111111Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
24191919222019201921202Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
363833343339Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
111311111112Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
1015101313777812102Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
9917310816914691918786981,148Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
911910126333369Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
423333333330Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
22222222218Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
424544444338Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
111112119Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111110
1151381011121010999
135312334227