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Peptidases • Penicillium flavigenum IBT 14082
Annotations/GenomesPenbi1Penbr2Pench1PenchWisc1_1Pendi1Penex1Penfe1Penfla1Pengl1Penja1Penla1Penox1Penra1Pensub1Penth1TotalAnnotation Description
Merops
4453312953172253703932884143592962563274253185,059
1689209111191211711101213169Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1111217Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
787949841011647107111Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
413733352834353041393633324334531Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
33233333252333344Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1111111111111114Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11111211111111116Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
111111118Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
64433363654235360Water nucleophile; water bound by Gln and Glu; all endopeptidases
65544454555555471Families of peptidase inhibitors not assigned to clans
11
211111119
1113
211111119
223233213141431
2233213122112328
95333785575868284Families of metallopeptidases not assigned to clans
1511101081310121410813112211178Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11111111111111216Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1113Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11891088710778591011128Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
323025281933302529223219292823404Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
101011116151711111376101511164Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
54432454434233353Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
111111111111113Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
21221123112119Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
201820221818211619212118191922292Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
106885139911108811129137Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1111111121213Serine or threonine nucleophile; N-terminal nucleophile
777657779757797104Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1931099295671321609317412896761071731021,797Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
91510941181591312691013153Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
44552532433353354Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
22222222232222231Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11114Serine nucleophile; catalytic residues in the order Ser, Glu, His
32111221212221225Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
2211121143232227Families of peptidases of unknown catalytic mechanism not assigned to clans
11111111111111115
16151013814981213108111310170
112116
11114
333233104632253153