Peptidases • Echinodontium tinctorium Aho-80 v1.0
Annotations/GenomesAmycha1Echtin1Lopni1Ricme1Scysp1_1Varmin1TotalAnnotation Description
Merops
3703544184403263382,246
292842512830208Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1121117Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
171725241820121Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
149151082581Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
62341218Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
773320Water nucleophile; water bound by Gln and Glu; all endopeptidases
22332214Families of peptidase inhibitors not assigned to clans
112
1111116
46457733
22112210Families of metallopeptidases not assigned to clans
222315191615110Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
151119Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11114Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
891211121163Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
141522251613105Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
991313131067Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1111116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
66655634Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11114Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
212021242220128Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
938114439Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
252018171614110Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
136138157162120120833Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
74772229Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
44343321Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1111228Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
65235425Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1111116
221922231515116
112
2215