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Peptidases • Pochonia chlamydosporia 170
Annotations/GenomesBeaba1Cormi1Metac1Metro1Myrin1Nieex1Pocchl1Pursp1Trire2TotalAnnotation Description
Merops
3653213304244394824564142863,517
222420291725222415198Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11114Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
23323423325Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
221817221729212121188Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
44333332328Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
111111118Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
12111111110Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1111318Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
1111116Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
7106518108661Water nucleophile; water bound by Gln and Glu; all endopeptidases
32343432529Families of peptidase inhibitors not assigned to clans
11
1124
11
221221212
212511113
22
23578713137Families of metallopeptidases not assigned to clans
261915292124382711210Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
334314343340Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
2112222113Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
7119111010119886Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
202015183524232318196Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
141216181827201813156Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
44444434435Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11111117Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
11Asparagine nucleophile; all self-processing endopeptidases
12710292474176Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
212221242424262323208Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
54688677455Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
44343353433Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
322734402618283614255Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1048187114176207158137921,156Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1615171571729196141Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
33333332225Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1111111119Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11136Serine nucleophile; catalytic residues in the order Ser, Glu, His
33123212320Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11114Families of peptidases of unknown catalytic mechanism not assigned to clans
111111118
12813141510101715114
11114
31432132221