Peptidases • Mycena latifolia 10383 v1.0
Annotations/GenomesMyc59_1Mycalb1Mycale1Mycami1Mycbel1Myccro1Mycepi1Mycfil1Mycflo1Mycgal1Mycgale1Mychae1Myclat1Myclep1Mycmac1Mycmet1Mycoli1Mycpol1Mycreb1Mycros1Mycrub1Mycsan1Mycvit1Mycvul1TotalAnnotation Description
Merops
6729226795904316608957426031,0519904758611,3125908341,6688831,1208239268106671,03620,240
5688687545689177391158849911365783171848979886975761,957Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
22Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
242211912102267354443315891Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
22Water nucleophile; water bound by two Asp
42382930223449433346582840863150114446551414033991,146Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
1611958936165211171434201224131413178917349Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
34241622324111062742323680Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile: catalytic residues in the order Cys, His in sequence
1113Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
45441586281246971162891314412164Water nucleophile; water bound by Gln and Glu; all endopeptidases
345433333333393114436333496Families of peptidase inhibitors not assigned to clans
112
2114
1111211111111115
314
211131112111111120
4104947465675121065208465776167
21136255614137258351592345126153Families of metallopeptidases not assigned to clans
283920192745253333341619345314215435655034182658800Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
2222211371111121211236Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1121111132111114111111130Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
21121111112121112111111129Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1212131211910111314141192611121714181312111317315Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
363833241931262419503918444525415227603435261935800Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
252215181318251915292517424022183725262223222628572Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11111111211111111111111125Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
311311221117241661255Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
976766117619136616971079795637231Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1111111119Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
2211121111Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Asparagine nucleophile; all self-processing endopeptidases
211112222211244132438Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
282835262135314143513724315023434043463629343442851Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
71291016121711251275109811231398141076271Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
32332612113132112321512253Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
428762312840705721105113337411844871725710863799842821,713Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
2734283012401652603913072784144261943705402413487494154733404113672844278,642Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
20292620921252810393411185017325027542935241931658Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
6543445745746443115654564121Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
11131133111111113111111132Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11114Serine nucleophile; catalytic residues in the order Ser, Glu, His
5654354444844844761155344121Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
21111211212Families of peptidases of unknown catalytic mechanism not assigned to clans
11111111112111111111111125
311510161317281514183216173017124519192332171319488
1111116
1113
112115121241221128