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Peptidases • Fusarium sp. FSSC 10 v1.0
Annotations/GenomesFusco1Fuseq1Fusfu1Fusgr1Fusox2Fusoxy1Fusoxys1Fusps1Fusre1Fusso1FusspF10_1Fustr1Fustri1Fusve2Fusven1Necha2TotalAnnotation Description
Merops
4744034913987105175333765105523354464575774065477,732
21212218262325152221161719232020329Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1124Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
5373137726864782997Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
20182217422222172124211819331822356Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
233492332322383355Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11511211Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111121111111121219Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
1111111111121115Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
211311351121325Water nucleophile; water bound by Gln and Glu; all endopeptidases
333393333333353356Families of peptidase inhibitors not assigned to clans
11221119
2114
222221221222222230
21222221232232230
627188819836671586Families of metallopeptidases not assigned to clans
18161917231923141821142320231520303Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
666567666556666593Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1111162211111121134Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
88109268997997617813163Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
31283429453531283131243229332635502Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
24222317312624172730111918262028363Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
444454444444444465Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
432264623643334560Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
20232324352122232225232326342426394Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
1171281788710767711814148Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
343333332223333245Serine or threonine nucleophile; N-terminal nucleophile
25152121232229202318181720231919333Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
2161712201682882482451622442421212022112451792393,401Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
14141515191318142035161713181431286Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
333343332333333348Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
111131111112111119Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
516Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
111111111111111116Serine nucleophile; catalytic residues in the order Ser, Glu, His
233332432323333345Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1112117Families of peptidases of unknown catalytic mechanism not assigned to clans
111161111111111121
14121212171315119149911181113200
111111118
1243312812332742