Peptidases • Mortierellomycotina
Annotations/GenomesDisorn1Lobtra1MoeNVP64_1MorAD185_1_1MorGBAus27b_1Moramb1Morcap1Morel2Morel_U14_1Morgam1Morhum1Mormin1_1Mormul1Morve1Morwol1TotalAnnotation Description
Merops
3212943583672862742494053503613113482733222404,759
351735111311133631332326172512338Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
112Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
55555335553555367Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
332928392524212529262528242722405Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
66866557766555487Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1112121313222123Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1111116Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
17211214Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
1111111111111114Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
111115Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
878773388976975102Families of peptidase inhibitors not assigned to clans
111123110
2111111111112
11114
11
23263221231332237
11111211113212221
14122211221111224Families of metallopeptidases not assigned to clans
162038311826262835312035172318382Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
53543544565655469Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
42223222223232235Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
33333333333333345Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1110111111991012111213111211164Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
12171312141311131314912121515195Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
667565577116766595Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11111111111111115Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
23433333321332341Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
26113221111223Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
221921201816162019201919182016283Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
46556456546536575Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
11Serine or threonine nucleophile; N-terminal nucleophile
11141311Families of serine peptidases not assigned to clans
171715342420171916202934172415318Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
7972886471676295868066765775551,093Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
109205596182025241610225204Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
45465555455745574Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
11131111111111117Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
34354534233341249Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111111111114
221819632314127019261717261414374
111115
11