Peptidases • Lollipopaia minuta P26; CBS 116597 v1.0
Annotations/GenomesConlig1Crypa2Lolmi1Phaal1TotalAnnotation Description
Merops
3733773253581,433
2527212093Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
613414Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1529252493Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
444416Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
12216Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11114Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1113Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
484420Water nucleophile; water bound by Gln and Glu; all endopeptidases
11114Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
434415Families of peptidase inhibitors not assigned to clans
11
21227
414413
123
232310Families of metallopeptidases not assigned to clans
2013141966Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
21238Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
12227Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
91010938Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
2122212387Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1315122161Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
333312Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11114Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
2114Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
28242325100Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
734721Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
112Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
12216Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
2520172587Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
135137102106480Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1088733Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
334212Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
12115Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1124Serine nucleophile; catalytic residues in the order Ser, Glu, His
542213Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11125Families of peptidases of unknown catalytic mechanism not assigned to clans
11114
815131551
112
11
334414