Peptidases • Schizophyllum commune ZB1 v1.0
Annotations/GenomesSchco2071_1Schco2231_1Schco2251_1Schco2271_1Schco2272_1Schco3SchcoZB1SchcoZB2Schco_LoeD_1Schco_TatD_1Schrad1TotalAnnotation Description
Merops
3233243313283323453373303363424143,742
2124272525293525273042310Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1222222232222Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
2021212218202020181925224Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
4363454465953Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
112322221218Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1111111111111Water nucleophile; water bound by Gln and Glu; all endopeptidases
2222322222223Families of peptidase inhibitors not assigned to clans
121222222218
6677777776976
3333333333333Families of metallopeptidases not assigned to clans
1918202120221919232222225Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1111221211215Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11111111210Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1111121111112Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1010910910101091110108Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
2123222222232321212230250Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1112111112121111121114128Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1111111119Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
5555655656760Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11114Asparagine nucleophile; all self-processing endopeptidases
2421232223222223212325249Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
86668788691183Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1111111111111Serine or threonine nucleophile; N-terminal nucleophile
6666666666767Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1311291291291321321271271311321521,451Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
3422233344232Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3333333333333Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1111111111111Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
4344444443644Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1111111111212
1212131112121112141218139