Peptidases • Trypethelium eluteriae v1.0
Annotations/GenomesCenge3Clagr2CocheC5_3Hyspu1Lepmu1Mycgr3Sepmu1Tryvi1Xanpa1TotalAnnotation Description
Merops
3343722603422863561,950
182910221019108Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
213Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
312445331Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
302822272526158Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
34523421Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
212319Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11114Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1113Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
1111116Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
35252421Water nucleophile; water bound by Gln and Glu; all endopeptidases
55454528Families of peptidase inhibitors not assigned to clans
1121117
13533621
563211027Families of metallopeptidases not assigned to clans
14111128181294Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
17643223Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
2111117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
6661010846Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
182621171915116Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
12913691261Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
33343319Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
3232212Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
222022212124130Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
79562332Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
111115Serine or threonine nucleophile; N-terminal nucleophile
14161016112693Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
931328011997138659Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
85286635Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
43333319Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
22233113Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
33334319Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
22Families of peptidases of unknown catalytic mechanism not assigned to clans
1111116
441589111198
23121312