Peptidases • Laccaria

Within the framework of the JGI Mycorrhizal Genomics Initiative (MGI), we are sequencing a phylogenetically and ecologically diverse suite of mycorrhizal fungi (Basidiomycota and Ascomycota), which include the major clades of symbiotic species associating with trees and woody shrubs. In addition, we are re-sequencing genomes of Laccaria bicolor to get insight into the historical microevolutionary forces driving the genomic evolution of symbiosis-related genes.

Annotations/GenomesLacam2Lacbi2LacbiD101_1TotalAnnotation Description
Merops
324338662
303262Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
224Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
162945Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
4913Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
314Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
101121Families of peptidase inhibitors not assigned to clans
181836
224
325
336Families of metallopeptidases not assigned to clans
181735Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
112Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
145Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
347Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
111223Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
101626Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
8917Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
5914Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
212344Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
121224Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
213Serine or threonine nucleophile; N-terminal nucleophile
101020Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
7874152Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
527Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
347Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
112Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
4610Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
112
372158