Peptidases • Cortinarius aff. campbellae TAS5-PSC4363 v1.0
Annotations/GenomesAgrped1Bolvit1Corcam1Corgl3Crafun1Crevar1Galma1Gymch1Hebcy2Hypsu1Panpap1Phoaln1TotalAnnotation Description
Merops
4543353293123353563883862863793993834,342
421930343017275016381519337Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
2112111121114Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
211320201515202017171220210Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
118167651076941099Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2231513121324Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
12126Water nucleophile; water bound by Gln and Glu; all endopeptidases
343331193553355Families of peptidase inhibitors not assigned to clans
213
11
1132222215
961456345610665
23323222123227Families of metallopeptidases not assigned to clans
463811103337282024244432347Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1111311116118Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11111111111112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11131111111114Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1091399911989129117Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
202912101915151315172021206Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1111111299121011121011129Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11121111111113Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
121127Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
55555565555662Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
112Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
222421191920222421202023255Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
187158711106712137121Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
112Serine or threonine nucleophile; N-terminal nucleophile
151522151720221416202514215Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
165111111104111127142144911411551551,557Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1088479111268127102Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
33333443433440Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
213Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
11111111111112Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
43444444444447Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11111111111112
211311241411182213131313186
22