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Peptidases • Kazachstania africana CBS 2517
Annotations/GenomesAscru1Aspnid1Canar1Canca1Canta1Dekbr2Hanva1_1Kazaf1Klula1Lipst1_1Metbi1Picpa1Sacce1Spapa3Wican1Yarli1TotalAnnotation Description
Merops
1552911411481491431111221272001421281371571822122,545
1041241566851012108181235175Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
426Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
13312111141Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
14101216131511161322141115141814228Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
932123322222234244Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11112118Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; active peptidase is a homodimer with active site His and Glu from one monomer and Cys from the other. Catalytic residues in the order His, Glu, Cys in each monomer.
1111116Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
44Water nucleophile; water bound by Gln and Glu; all endopeptidases
453243222344244351Families of peptidase inhibitors not assigned to clans
11
112
11
112
131111221211219
22222332322324236
17111111211111122Families of metallopeptidases not assigned to clans
9168966667106679610127Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11111111111111115Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
12211311212111222Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
6568776647765767100Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
8401013121411913101189101913210Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
586339215543436471Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
31444411432233443Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
19171620181816182019161820171920291Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
4323141423823444Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
111111111111214Serine or threonine nucleophile; N-terminal nucleophile
74363343263331041478Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
31613029332721242660292625284444538Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1113111111113Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
413333333333333347Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1212219Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
323214123523234242Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
32117Families of peptidases of unknown catalytic mechanism not assigned to clans
11111111111111115
88610911788131199101013150
11
112
11231210
22
3811141