Peptidases • Blakeslea trispora NRRL 2456 v1.0
Annotations/GenomesBacci1Blatri1Lichy1Mucci2Phybl2Rhimi1_1Umbra1TotalAnnotation Description
Merops
4222513113042842532722,097
31182524282022168Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1033444331Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
40263535292924218Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
655676237Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1631232229Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
112Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1121128Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
212121110Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
937767645Families of peptidase inhibitors not assigned to clans
11
111115
1113
11
12126
88
12111219
523211115
11111117Families of metallopeptidases not assigned to clans
26231623171822145Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
22Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
3115Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
445434327Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1511111312141187Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
167171115111794Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
115712961060Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1112117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
743656233Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
322111313Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
35182023171718148Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
445333325Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
112Serine or threonine nucleophile; N-terminal nucleophile
22151510191110102Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
96508267554671467Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1131118Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
744546333Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
33Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
221331214Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1116776442Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
21111118
26222324262417162
1113
11
11