Peptidases • Aspergillus calidoustus
Annotations/GenomesAspcal1Aspfu1Aspni_NRRL3_1Aspnid1Aspor1TotalAnnotation Description
Merops
4752744042914141,858
941541345Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
514212Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
281933677Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
2350371034154Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3343316Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1124Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
112Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile; active peptidase is a homodimer with active site His and Glu from one monomer and Cys from the other. Catalytic residues in the order His, Glu, Cys in each monomer.
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
2254316Water nucleophile; water bound by Gln and Glu; all endopeptidases
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
6755427Families of peptidase inhibitors not assigned to clans
112
11
11
11
11
22138
524112
11
1513771456Families of metallopeptidases not assigned to clans
231315162592Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
21126Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
64105732Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
3917284026150Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1471681358Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
3351113Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
11Asparagine nucleophile; catalytic residues in the order Asn, Glu in sequence; all self-processing endopeptidases
4239Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2020201726103Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
6694934Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
1124Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
88134942Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1745916461153611Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
111111731Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3321716Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
3522315Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
112217Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
4223920Families of peptidases of unknown catalytic mechanism not assigned to clans
111115
12111081960
213
11
112
341838393