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Peptidases • Dichomitus squalens LYAD-421 SS1 v1.0
Annotations/GenomesCersu1Dicsq1Hetan2Phchr1Pospl1SerlaS7_3_2Serla_S7_9TotalAnnotation Description
Merops
3404073041963621,609
4144342081220Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1010Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
111216Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
13161881974Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
7676430Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
351211Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
33Water nucleophile; water bound by Gln and Glu; all endopeptidases
2222210Families of peptidase inhibitors not assigned to clans
11
11125
3342113
2234213Families of metallopeptidases not assigned to clans
91513111563Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
213Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11114Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
112Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
9894838Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
13131331557Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
11151481765Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11114Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
112Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
6651523Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
123Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
17222282089Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
6743424Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
24321910994Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1361369675101544Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
2525418Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3436319Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
111115Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
3554522Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1113Families of peptidases of unknown catalytic mechanism not assigned to clans
11114
2152161120120
112
11