Peptidases • Scheffersomyces coipomoensis NRRL Y-17651T v1.0
Annotations/GenomesCanalb1Canta1Cante1Clalu1_2Debha1Lodelo1Metbi1Metfru2Meygui1Picst3Schcoi1Schque1Spaarb1Spapa3TotalAnnotation Description
Merops
1501491511531511281422581701481451481561572,206
19151020611122516121091918202Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1111111119Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1513131113101417161211121814189Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
2222222223223331Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1113Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111111111111113Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11Water nucleophile; water bound by Gln and Glu; all endopeptidases
4444334744444457Families of peptidase inhibitors not assigned to clans
11111131111114
2222222212232228
112111121111115Families of metallopeptidases not assigned to clans
5661056616895579103Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
111111111111113Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1111111911111122Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
77787571285667799Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
101214101410111614101313910166Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
3374424683433357Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
2442323333233340Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
213Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
1918181718191631191718191817264Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
3331652622111238Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11111211111113Serine or threonine nucleophile; N-terminal nucleophile
43333337336451060Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
3233343036242954393532343128471Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1111411112111118Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
2334333532333343Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
112Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
2122322322333333Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111111111114
8999109112110810101010144
11
2213113326451236
11