Peptidases • Zoopagomycotina
Annotations/GenomesPipcy3_1Piptie1Synfus1Synplu1Synps1Thasp1TotalAnnotation Description
Merops
1411693252852292401,389
23332316Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1431312Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
11142217152099Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
42665528Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
21142212Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1113Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
1113Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
23432317Families of peptidase inhibitors not assigned to clans
11
112
1113
112
21126Families of metallopeptidases not assigned to clans
121138352535156Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
2743622Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
111115Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
2223211Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
887136547Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
891911111068Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
45564529Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111115Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
21545320Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Water nucleophile; water bound by two cobalt ions ligated by Glu, Glu, His, His, Asp
11Asparagine nucleophile; catalytic residues in the order Asn, Glu in sequence; all self-processing endopeptidases
431384436Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
131523192518113Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
34551523Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1111217Serine or threonine nucleophile; N-terminal nucleophile
61167462634190Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
314057575239276Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
44Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
34544222Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
2221119Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
47573430Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
111115
8121613161681
72716