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Peptidases • Xylaria cubensis CBS 116.85 v1.0
Annotations/GenomesAntav1Bisnum1DalEC12_1Entma1HypEC38_3Xylacu1Xylcas124033_1Xylcube1Xylcur114988_1Xylhyp1Xylpal124036_1Xyltel121673_1TotalAnnotation Description
Merops
4483443553583753753703954023893403904,541
211815181621191618191818217Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1113Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
36424344533546Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
281722232225232324222722278Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
35434344443445Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
22121111111115Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11112111211114Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11114Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
33524222232232Water nucleophile; water bound by Gln and Glu; all endopeptidases
64444444455452Families of peptidase inhibitors not assigned to clans
1113
22221122112220
43636455553453
126444468754973Families of metallopeptidases not assigned to clans
201917181718201719151820218Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
54555655555560Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
21211212212219Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
9981081110101010910114Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
262523232525222729242625300Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
131718161716161616151116187Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
33334343353340Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11111111111112Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
11112122415Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
232324232124222424222120271Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
63466554653457Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1113Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
21121222222221Serine or threonine nucleophile; N-terminal nucleophile
242122162218151515171717219Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1781121191221401291341501481501201461,648Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1568121014111512161014143Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
34443333332338Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
21121211222118Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
111112211112Serine nucleophile; catalytic residues in the order Ser, Glu, His
43334444342442Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
31122121114Families of peptidases of unknown catalytic mechanism not assigned to clans
21111111111113
161414181313121413141213166
11
11
34335546743653