Peptidases • Grosmannia clavigera kw1407
Annotations/GenomesFusox1Grocl1Maggr1Necha2Neucr2Thite2Trire2Verda1TotalAnnotation Description
Merops
2393375472422562863062,213
11182019261513122Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1214Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
329533227Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by Asp and His; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
16152216152117122Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
333333220Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1211117Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11211118Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
111115Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
51324621Water nucleophile; water bound by Gln and Glu; all endopeptidases
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
343355326Families of peptidase inhibitors not assigned to clans
11
12232212
162141318
235211115Families of metallopeptidases not assigned to clans
923201291119103Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
145223825Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
2121129Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
78131088761Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
18193514111826141Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1162810913986Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
22Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
334444426Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
351211Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
19212623202325157Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
3414234333Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
1247Serine or threonine nucleophile; N-terminal nucleophile
2114Families of serine peptidases not assigned to clans
16201989141399Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
74120239718692110792Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
5331576562Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
333232319Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1111116Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
213Serine nucleophile; catalytic residues in the order Ser, Glu, His
233423320Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
171211Families of peptidases of unknown catalytic mechanism not assigned to clans
11121118
911131314151388
22
38712223