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Peptidases • Clavispora lusitaniae ATCC 42720
Annotations/GenomesAscru1Aspnid1Canar1Canca1Canta1Clalu1_2Dekbr2Hanva1_1Klula1Lipst1_1Metbi1Picpa1Sacce1Spapa3Wican1Yarli1TotalAnnotation Description
Merops
1552911411481491531431111272001421281371571822122,576
10412415206651012108181235187Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
426Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
133121111142Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
14101216131115111322141115141814223Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
932122332222234244Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11112118Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; active peptidase is a homodimer with active site His and Glu from one monomer and Cys from the other. Catalytic residues in the order His, Glu, Cys in each monomer.
11111117Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
415Water nucleophile; water bound by Gln and Glu; all endopeptidases
453244322344244353Families of peptidase inhibitors not assigned to clans
11
112
11
112
13111221211218
22222232322324235
17111111211111122Families of metallopeptidases not assigned to clans
91689610667106679610131Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11111111111111115Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
12211131212111222Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
6568787647765767102Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
84010131210141113101189101913211Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
586334925543436474Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
31444241432233444Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
213Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
19171620181718162019161820171920290Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
4323111423823441Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11111111111213Serine or threonine nucleophile; N-terminal nucleophile
74363334263331041478Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
31613029333027212660292625284444544Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
11131111111114Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
413334333333333348Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
1212219Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
323212413523234242Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
32117Families of peptidases of unknown catalytic mechanism not assigned to clans
11111111111111115
88610991178131199101013151
11
112
112331213
22
3811141