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Peptidases • Uncinocarpus reesii UAMH 1704
Annotations/GenomesBlade1Cocim1Gymau1Gymci1_1Hisca1Micca1Triru1Uncre1TotalAnnotation Description
Merops
2342202242191742442391981,752
115109489561Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
111227Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
4423212422Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
2720252518222617180Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
2222223217Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
3321110Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
112116Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; active peptidase is a homodimer with active site His and Glu from one monomer and Cys from the other. Catalytic residues in the order His, Glu, Cys in each monomer.
1113Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
5464554336Families of peptidase inhibitors not assigned to clans
11
111115
112
1211122212
1112117
5226164228Families of metallopeptidases not assigned to clans
121513129161514106Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1221122314Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11215Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11114Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
12766577757Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
121215131012101195Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
6697567652Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
3333423425Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1221242115Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2219192021212317162Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
1333433424Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11114Serine or threonine nucleophile; N-terminal nucleophile
81964617172198Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
7061656750716849501Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
6564396645Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3523222120Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
2222232217Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1222122113Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
111111118
11
87887107863
11114
11
112
133135117