Peptidases • Saccharomycetales
Annotations/GenomesAmbph1Artfe1_2Arxad1Ascru1Ashgo1_1Babin1Botmuc1Canalb1Canar1Canbo1Canca1Canta1Cante1Cepal1_1Cepfr1_1Citma1Clalu1_2Cybja1Debha1Dekbr2Hanpo2Hanva1_1Hypbu1Isori2Issori2Issorie2Kazaf1Klula1Kurca1Lipst1_1Lodelo1Metbi1Metbi_SCcombMetfru2Meygui1Myxme1Nadfu1Nakbac1Nakdel1Nakwi1Ogapa1Pacta1_2Petxy1Pickud1Picme2Picpa1Picst3Sacarb1Sacca1Sacce1SacceM3707_1SacceM3836_1SacceM3837_1SacceM3838_1SacceM3839_1SacceYB210_1Satdi1Schcoi1Schque1Schsti1Spaarb1Spapa3Spola1Sugame1Symat1Torde1Tripe1Wican1Wicdo1Yarli1YarliW29YarliW29_1YarliYB392YarliYB419YarliYB420YarliYB566YarliYB567YarliYlCW001Yarlip1Zyghe1_2Zygro1TotalAnnotation Description
Merops
15316020615510717114015014113414814915116116417815316715114315111115313714414012212716020012814211525817016715911712313915515216313413412814812716913713613513713613514311514514815315615715320020811819018215721221721621521821621521621821418412312,860
153121107126191211415101417202014665610810885910111252516166691051088610124358999998171091319187192451912103539363838383738393614101,204Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1211218Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
111113112111111111131111111111111111121111222112159Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1215211414171715121216131316141711161315141115151615161315221014121716181613131114131315131112141415151515151517121112121814191220131718161414141414141414141418121,175Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
432924222212234222233342222232222222322222322232322222222223333332342222222222222195Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1112111111121121121112211132Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111111111110Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
111111111111111111111111111111111111111140Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11121118Water nucleophile; water bound by Gln and Glu; all endopeptidases
423424343224433244334232222253344744522444322442322222222444444462443333333333332255Families of peptidase inhibitors not assigned to clans
11111111111111115
11111117
11111111111111115
11211111111111111112121131122112112222222221111111221122222222222196
222222222222242323222321113223221211222122212223133333311232222322242222222222222169
1111111111112111111111111111211121211111111111111111111111112211111111111111183Families of metallopeptidases not assigned to clans
11610971395899665661065666116766761066516887566676666978777777765577961311512610109109999999136619Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11111111111111131111111111111111111111111111111111111211111111111111111111178Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1121122121211112111123112211221119135222221212111111121111112211312222222222211129Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
112Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
7786477766877788877786688864675771286766786688655755555555665777695766777777777775535Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
13111789149101091312141518171019141413111210111291317101011916149151091613142011118101011910101010101051313109108141411131914131414141414141414141911992Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
8345244367337448474992466615105243684432689967334244444454433335453466444444444475380Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111111111110Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
22431232444444432534333331134233333412344335232222222222233335552534444444444432247Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
112Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
121111121112Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
1617211917161619161920181819182317181818181618181918182020191916173119202018171519181918191817211820202020202021161819171817182018181919212019211820191919202017191,516Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
4151223332333231361323434114522623321242333323286565652112122323333444444444341242Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
22Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
1111111111111111111111111112111111111111111111111111111111122222222221182Serine or threonine nucleophile; N-terminal nucleophile
44471394326333333533344322322633373343433442333363333333264351034534431415141516151515151543407Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
3028513116452332302329333433363530323627332135262828242634602429225439332422243134293627242635243025262526262525203234393128335448234644294446464646464646464637212,671Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
12111113112214121131111111112311121122111111111165Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
333433323333333343333333333343333533433333333323333333332333333333333333333333333246Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11114Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
1111121122111111111123Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11111117Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
222323423221243423342123342325222324522334332322322222221332333462443222222222262215Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
122111111111111111111111127Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111111111111111121111111111111111111111111111111111111111111111111111111180
810138971186101099118999101197981098881391182110131491071098789888988888118101081010111213813101113121212121212121212129797
11111111111111115
3111122131111323211216456121160
22
1113111111111111119