Peptidases • Hydnum rufescens UP504 v2.0
Annotations/GenomesBotbo1ClaPMI390Hydru2Rhiso1Tulca1TotalAnnotation Description
Merops
3744302774273531,861
4844294144206Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
22Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
414110Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
192018211795Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
1134121242Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
414514Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
77Water nucleophile; water bound by Gln and Glu; all endopeptidases
6552220Families of peptidase inhibitors not assigned to clans
9211
112
1225
5236117
2233212Families of metallopeptidases not assigned to clans
2114154119110Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1214Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11215Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1214Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
7988941Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
201417291292Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
11138141056Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11114Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
5657629Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
112Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2325372221128Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
58511736Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
112Serine or threonine nucleophile; N-terminal nucleophile
291912338101Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1021596712577530Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
12174538Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3333517Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
111115Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
5333620Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
145Families of peptidases of unknown catalytic mechanism not assigned to clans
111115
1747162370173
11
1113
213