Peptidases • Rhizopus microsporus ATCC11559 v1.0
Annotations/GenomesBacci1Hesve1Lichy1Morel1Mucci2Phybl2Rhich1Rhimi1_1Rhimi_ATCC11559_1Rhimi_ATCC52814_1Rhior3Umbra1TotalAnnotation Description
Merops
4223113042843762532382322902722,982
31252428352020203322258Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1034454344344Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
40353529452930282824323Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
656786464254Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
161233221232Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
112Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1211128Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
221221112115Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
97761277713681Families of peptidase inhibitors not assigned to clans
11
112116
112
11
2125
111122112113
532111112118
11112111110Families of metallopeptidases not assigned to clans
26162317281815151822198Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
22Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
3411110Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
454384444343Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
15111312161411121311128Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
16171115141111101617138Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
117129565441073Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11212111111Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
7365106566256Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
321121111316Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
35202317311719193218231Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
453353223333Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1113Serine or threonine nucleophile; N-terminal nucleophile
221510191511881810136Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
96826755704652485371640Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1312111111Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
745476552348Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
314Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
213311121217Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1167796544463Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
2111117Families of peptidases of unknown catalytic mechanism not assigned to clans
211121111112
26232426242420172317224
1113
11
11