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Peptidases • Cantharellales sp. MUCL 035158 v1.0
Annotations/GenomesBotbo1Cananz1Hydru2Rhiso1Tulca1Tylas1TotalAnnotation Description
Merops
3743482774273533802,159
483029414468260Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
22Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
441110Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
191418211720109Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
11241212243Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
4445118Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
32831Water nucleophile; water bound by Gln and Glu; all endopeptidases
63522422Families of peptidase inhibitors not assigned to clans
9211
11
11
212218
52361522
24332216Families of metallopeptidases not assigned to clans
212215411912130Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
112116Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1112117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1214Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
77889847Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
201317291211102Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
11881410859Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
121116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
56576635Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
112Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
232637222124153Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
555117437Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1113Serine or threonine nucleophile; N-terminal nucleophile
29551233841178Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1021096712577100580Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
12451132Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
34335321Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1111116Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
54336324Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
44Families of peptidases of unknown catalytic mechanism not assigned to clans
1111116
171516237010151
11
112
12126