Peptidases • Lentinula edodes Le(Bin) 0899 ss11 v1.0
Annotations/GenomesGyman1Gymear1Gymlu1Lenafn1Lenedo1Lenlat1Lenrap1Ompol1Rhobut1_1TotalAnnotation Description
Merops
6154905613493343313452514613,737
564155343031272029323Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
21333331221Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
302423151916171821183Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
8611655462778Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
845213629Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
101112999131882Water nucleophile; water bound by Gln and Glu; all endopeptidases
62312981081784Families of peptidase inhibitors not assigned to clans
11
1113
111111118
84644443744
3432222523Families of metallopeptidases not assigned to clans
171512121411111413119Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
112Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
4111111212Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
72211111521Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
131010107101081593Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
272422151515151522170Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
14151514161516816129Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111111118Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
216321318Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
75588654654Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
22Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
252523272726281725223Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
111212654661072Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
442730131112161230195Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
238182190125117121126951581,352Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1415433321752Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
23432231424Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
111111219Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
54444444336Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
111111118
482387161514151324255
11