Peptidases • Mucoromycota
Annotations/GenomesAbsrep1Amyrou1Bacci1Benpoi1Blatri1Blatri_F921_1Blatri_F986_2Chlpad1Chocucu1Cirumb1Cokrec1Cunech1Dicele1Dicrob1Disorn1Ellano1Endsp1Fenlin1Gigro1Gilper1Gloin1Gonbut1Halrad1Helpul1Hesve2finisherSCJimfl_AD_1Jimfl_GMNB39_1Jimlac1Kircor1Liccor1Lichy1Lobtra1MoeNVP64_1Morel2Morel_U14_1Mormul1Morve1Mucci2Muccir1_3Mucmuc1Mycafr1Parpar1Phaart1Phybl2Phybla1Pilano1Pilumb1PnitS607_1PnitS608_1PnitS609_1Radspe1Rhice1_1Rhich1Rhidi1Rhiir2_1RhiirA1_1RhiirA4RhiirA5RhiirB3RhiirC2Rhimi1_1Rhimi_ATCC11559_1Rhimi_ATCC52814_1Rhior3Rhisto1Sakvas1Spifus1Spoumb1Synrac1Thaele1Umbelo1Umbisa1Umbra1Umbsp_AD052_1Zycmex1Zyghet1TotalAnnotation Description
Merops
34230242225225125425731625832724731828830932128522733749326430726725827928328528230736730531129435840535027332230428030123326532328427626124026727427726423037626727333127729328528025323823229030523922925528329429027427227733430222,151
26303120181918232423212224253523113485241224222126131412362625173536311725242225161924283119163032321973568121191111202020333713193220232422222324311,758Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
111115Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
43104333432333353322343476544463555555446332444345532521111214344533444323344276Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
112Water nucleophile; water bound by two Asp
353440302626263327282234272833322032522631282730273127323632352928252924273530312330312928302825282731274530292931302827293028283227232431342524242434312,239Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
676555565667676714566444641211186456877556656567856771053844434436464855566222255441Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
21623231332222112333113321311113122222233342222123555444422122124332312178Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111111111111113Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile: catalytic residues in the order Cys, His in sequence
121111111122121111111211221111111111111112111123221165Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
322112112121211221212121111111221121212211222222222111221221211298Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
112Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
9119735483775778746465657547598778889777837665764446512547565577713954567666687485Families of peptidase inhibitors not assigned to clans
11111117
22
1111211321111111111112111111134
1111121111111121111122
1111111119
11121122213111123211311122222147
11
89101111131155
2211222222121123121211211132123212121111122212111111211222113111111101
315222222411331224222222115331111122322341133111311112121142331344139
11
11
111111111111111111111111111411211111111111111111211111111111111111111175Families of metallopeptidases not assigned to clans
171926182322221728171714192916231420191720121319121720211916162038283517232321231520161715201917151717132814152315232120181515182017141815261615222018241,461Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
531323545551222250Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11Water nucleophile; water bound by single zinc ion ligated to His, Asp and His
1331412153372222321111441323223112212286Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
4444444344434434342473343523445333333445445334433333845564544444433444333346291Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
15131510111010121111911131211128146127101114111010101291110111012111213131012121212131212131313125166776666141112131391291112101011101212825Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
171616977714817813121612111415108121312101116161815191717131313121511111191020151310813121310914121518131314141111101614611121410161617162412983Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
135116555955598768667788126876108776777661287776987687856567966886544456687129101256539Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1112111111211112111111111111311111111221111111111111211111111111111121111284Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by two zinc ions ligated by Asp, Glu, His, His, Glu
1113Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
76744444454555242535425536377333433326554555555444441044444446566645436342355336Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
123Water nucleophile; water bound by two cobalt ions ligated by Glu, Glu, His, His, Asp
111115Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Asparagine nucleophile; all self-processing endopeptidases
5132215222412427431212233632232111122321122111232101111911671111111112443331279Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
333235201817183017252121182222241319241627222320212324233620201921201918202324191921211718191918182019183119202520262321171919322820192320202019181924251,641Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
44434432324712435233623235531035656536335333334345426554944443223542224323324284Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11512213324328Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
111111111111111111111122Serine or threonine nucleophile; N-terminal nucleophile
1135Families of serine peptidases not assigned to clans
12172271518201915289151414171072511111710911712161412141517151916172410921811191919711161515151315211921211917221188181715911111111710818141,101Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
8559965650514875469360846677796268931235178746670807574729277827288958657756763664961865556574856565659647074788476828275465248535456505776677978717394695,278Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
11111131110113822322114392018201022112115212222823221111211241207Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
4374444335354344458474364234574545445546574447355444744744446552443437333348337Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
31116Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
212122111211211211111111231211111111341213321111111122222221121111111122321110Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11114Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
951151246355108536195638549222876434241767649775646655944343246544686475454565390Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
213111111112111111111111111132Families of peptidases of unknown catalytic mechanism not assigned to clans
112111121111111111111111112321111111111111111111112111111111111111111177
212026222221202019211825282522201319162017152019232120242420231819701926142417222520192620182023232327142417121515161415242017232717202123201817171421151,573
11
11
1112211121311111111111111222137
11
111411110