Peptidases • Septobasidium sp. PNB30-8B v1.0
Annotations/GenomesAgahy1Chiap1Croqu1Eryha1Hetpy1Hyabl1Melli1Mellp1Mixos1Pucgr1Pucst1Rhoba1_1Rhomi1Rhosp1Sepsp1Sporo1Trisp1TotalAnnotation Description
Merops
1781971922321721811781832241851871652531581742,859
1119271312123930141014933117261Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
21151111223212126Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
201819182221141122201315201617266Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
33223332323222237Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1421211113Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111111111110Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
111115Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
33322222232233337Families of peptidase inhibitors not assigned to clans
111115
112
111115
23232231331241133
111111111111113Families of metallopeptidases not assigned to clans
1095668107111097111016135Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
2111111211214Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11136Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1111111221111116Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
66667744776767591Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
81071488461411139795133Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
565116655910810585104Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11111111111112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
65564674575555580Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11114Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11114Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
191723191819171726182017201817285Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
32122213222233131Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
111115Serine or threonine nucleophile; N-terminal nucleophile
2473335816121521375Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
465354864449436052475642893343797Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
216223241528Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
33343332253334448Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
21112121211217Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
34242214144322240Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111111113
1214111213129918111214211411193
2114
11
11136