Peptidases • Blastocladiomycota
Annotations/GenomesAllma1Blabri1Catan2Parsed1TotalAnnotation Description
Merops
4322162502831,181
51118Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
41229Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
43191524101Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
1489132Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
23128Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
21115Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
112Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
10711432Families of peptidase inhibitors not assigned to clans
213
22116
2114
21115Families of metallopeptidases not assigned to clans
57221721117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
6811429Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1065324Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1688638Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
21791653Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1134826Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
767323Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
112Asparagine nucleophile; catalytic residues in the order Asn, Glu in sequence; all self-processing endopeptidases
123Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
3319191990Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
733316Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
22Serine or threonine nucleophile; N-terminal nucleophile
30175148146Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
86393649210Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
95115Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
1147729Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
22Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
511310Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
966627Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
22224Families of peptidases of unknown catalytic mechanism not assigned to clans
3115
2412121664
213
11