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Peptidases • Calycina marina TRa3180A v1.0
Annotations/GenomesAmore1Bissp1Cadsp1Calmar1Glalo1Hymvar1Lorju1Lorma1Oidma1Rutfi1Sclsc1TotalAnnotation Description
Merops
2565257252773694364124146223422774,655
1519311820293532361612263Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
111115Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
71117856910115695Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
2029372025282124332418279Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
4332234442233Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
121225311119Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1251221212120Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
2114Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
111111118Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2414253135241Water nucleophile; water bound by Gln and Glu; all endopeptidases
112Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
5454445554550Families of peptidase inhibitors not assigned to clans
112
22
123
22
211221221115
3472335463343
11
412103336683361Families of metallopeptidases not assigned to clans
93433152120151415118195Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1522221112322Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1211111111213Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
81111899991088100Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1840412226262726302317296Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
11162591417101118118150Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
4344444444443Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11114Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
372222222226Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2227272724222625292025274Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
27135666384464Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
21111121111Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
1323401515162226381412234Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
75204315761441911471572741441001,827Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
421305791592694139Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3433333333233Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1311121131116Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1225Serine nucleophile; catalytic residues in the order Ser, Glu, His
3332323423331Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11114Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111111111
1220301113121314241217178
123
11
2443335125