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Peptidases • Mortierella sp. AD185 v1.0
Annotations/GenomesDisorn1Lobtra1MorAD185_1_1Mormul1Morve1TotalAnnotation Description
Merops
3212943672733221,577
3517111725105Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
112Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
5555525Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
3329392427152Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
6665528Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11226Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1113Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
111115Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
8779738Families of peptidase inhibitors not assigned to clans
11
21115
112
2363216
111126
142119Families of metallopeptidases not assigned to clans
1620311723107Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
5345522Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
4223213Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
3333315Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
111011111255Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
121712121568Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
6656629Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111115Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
2333213Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
6118Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
221920182099Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
4653624Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
33Families of serine peptidases not assigned to clans
1717341724109Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
7972645775347Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1095102256Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
4564524Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
113117Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
3454117Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
111115
2218632614143
112