Peptidases • Polyporus brumalis BRFM 1820 v1.0
Annotations/GenomesDicsq1Gansp1Leisp1Lenti6_1Polar1Polbr1Pycsa1Tralj1TotalAnnotation Description
Merops
4073804124264434473763523,243
4448604452595449410Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1221222113Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1615141014121111103Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
6545574440Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
3121119Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
38113452238Water nucleophile; water bound by Gln and Glu; all endopeptidases
21023332227Families of peptidase inhibitors not assigned to clans
1111116
3233332221
2223332219Families of metallopeptidases not assigned to clans
1514162416181817138Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
111111118Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
111311210Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1113Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
889891011871Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1313161516161417120Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
151111111111111192Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11111117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
1113Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
6655566544Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2222222322222223178Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
76571095554Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
3225343930312925245Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1361281591801841871451421,261Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
53751174446Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
4434445331Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
111111118Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
5434444432Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11114Families of peptidases of unknown catalytic mechanism not assigned to clans
111111118
523514182720148188
1113