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Peptidases • Phyllosticta
Annotations/GenomesPcapi1Phcap1Phcapi1Phcit1Phcitr1Phy27169Phycap1Phycit1Phycitr1Phycpc1TotalAnnotation Description
Merops
2612632562712642542662552652672,622
18181815151717151714164Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
555534634444Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
24232325232325222326237Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
222222323222Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
111231121114Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1111111119Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11114Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
111453123324Water nucleophile; water bound by Gln and Glu; all endopeptidases
444545455545Families of peptidase inhibitors not assigned to clans
11
111111111110
1111111119
333222322325Families of metallopeptidases not assigned to clans
13141315121415121513136Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
111111111110Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
222222222220Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
787766767768Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
19181917181819181818182Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
999999810101092Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11114Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
333332333329Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
111126Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
19201920191818201918190Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
333333343331Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
111111211212Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
777777878873Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
90938991918691878690894Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
444633433539Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
333333333330Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
222222222220Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
433442444436Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1221118Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111110
9981112991010996
222233234326