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Peptidases • Aspergillus floridensis DTO 198-A8 v1.0
Annotations/GenomesAspflor1Aspfu1Aspni_NRRL3_1Aspnid1Aspor1TotalAnnotation Description
Merops
3322744042914141,715
1441541350Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11428Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
61933655Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
3350371034164Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3343316Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
21126Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1113Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile; active peptidase is a homodimer with active site His and Glu from one monomer and Cys from the other. Catalytic residues in the order His, Glu, Cys in each monomer.
6254320Water nucleophile; water bound by Gln and Glu; all endopeptidases
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
5755426Families of peptidase inhibitors not assigned to clans
11
11
11
11
12137
524112
11
1013771451Families of metallopeptidases not assigned to clans
101315162579Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11125Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
84105734Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
2717284026138Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1071681354Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
5351115Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
11Asparagine nucleophile; catalytic residues in the order Asn, Glu in sequence; all self-processing endopeptidases
235Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2020201726103Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
5694933Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
123Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
78134941Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1245916461153561Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
51111725Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3321716Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
2522314Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order Ser, Glu, His
212218Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
223916Families of peptidases of unknown catalytic mechanism not assigned to clans
111115
10111081958
11
112
21838361