Peptidases • Fennellomyces sp. T-0311 v1.0
Annotations/GenomesChlpad1Fenlin1Gonbut1Kircor1Liccor1Lichy1Mucci2Mycafr1Parpar1Phaart1Phybl2Rhimi_ATCC52814_1Synrac1Thaele1Zycmex1Zyghet1TotalAnnotation Description
Merops
3163372673673053113042332653232842322832943343024,757
23342436262524161924282020232431397Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
423463433244444458Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
33322836323535233031292831343431502Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
654645665676665588Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
121311222331241231Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11112211111111117Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
112121112112218Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
8669877376676787108Families of peptidase inhibitors not assigned to clans
112
111115
1113
2332132117
11
21211111211311120
242533223411424446
11111111111111115Families of metallopeptidases not assigned to clans
17201219161623152016171515261824289Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
31127Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
343445444534444665Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1214101291113121212121211121212188Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1415131519171191020151014102412228Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
96887712776948756116Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111311211111121221Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
452733645556365574Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
52132123211123130Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
30192236202023192121171920202425356Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
2221035333332242453Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
111115Serine or threonine nucleophile; N-terminal nucleophile
192510121415108111919811111814224Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
759374927782674961865548766794691,165Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
33143111514128Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
354574557445374880Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11111321332112124Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
6988767649747565104Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
3115Families of peptidases of unknown catalytic mechanism not assigned to clans
21132111111111119
20191524202324252019261723202115331
11
1231119
11
11