Peptidases • Xerocomus badius 84.06 v1.0
Annotations/GenomesBoled1Conpu1Gyrli1Hydpi2Leumo1Paxin1Pisti1Rhivi1Sclci1SerlaS7_9_2Suilu1Xerba1TotalAnnotation Description
Merops
5054324213933786063064222863463394,434
615918041431043864396146736Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
213Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
1121222221117Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
2025131816131516122218188Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
10977443644967Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
4112312212120Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
5425111991Water nucleophile; water bound by Gln and Glu; all endopeptidases
1125512712232465Families of peptidase inhibitors not assigned to clans
11
11114
123
2223722321430
2221222232222Families of metallopeptidases not assigned to clans
2417141111271512191114175Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
2112121111114Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1178871110988996Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1622161716211618171519193Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
141711131513913181514152Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1111111111111Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
2215Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
5655576566561Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11111117Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11111111122123Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
1918192222212021212122226Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
51044533524752Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
211127Serine or threonine nucleophile; N-terminal nucleophile
121989141258696108Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
90134761021051186710771114901,074Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
653311214228Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
4535434843548Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1111111111111Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
4432412345436Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111111111
12132341026921364106332243839
11
211116