Peptidases • Smittium culicis ID-206-W2
Annotations/GenomesCoere1Coespi1Kicala1Linpe1Marpt1Rambr1SmicuMNP_2SmiculW2_1Smimuc2Zancul2TotalAnnotation Description
Merops
2042231942722553693282812202472,593
4644612572555Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
13116Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
111311221114Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
20201629162224181315193Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
443358544848Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2232531119Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11111218Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
22Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
123Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
453533474442Families of peptidase inhibitors not assigned to clans
11
213
1135
121511235223
11111128Families of metallopeptidases not assigned to clans
1822142928191211611170Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1515Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
433336532739Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
343554973548Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
8878791197882Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
10101217122224262217172Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
56476743345Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11114Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
1113Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
33544632333Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
14181923253738383661309Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
18202221212042282119232Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
45554811134Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
1112117Serine or threonine nucleophile; N-terminal nucleophile
421444318181517126Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
49494361666271564742546Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1818Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
5333679105455Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
213Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
12211111111Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
13232422221Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
4116Families of peptidases of unknown catalytic mechanism not assigned to clans
111111212112
14171215151624211012156
2114
1113
123