Peptidases • Leptodontium sp. PMI_412 v1.0
Annotations/GenomesAcema1Cadsp1Glalo1Leptod1Marbr1Phisc1TotalAnnotation Description
Merops
5627253696572466483,207
343120331041169Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
141751781778Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
293725342326174Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
43243420Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2141210Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
25211314Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1124Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
1113Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
74452830Water nucleophile; water bound by Gln and Glu; all endopeptidases
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
45454527Families of peptidase inhibitors not assigned to clans
112
213
112228
67343528
112
7103102739Families of metallopeptidases not assigned to clans
163321281621135Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
12222110Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1111217Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
101191041256Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
344126401841200Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
19251423926116Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1113Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
44433422Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
111115Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
27253322Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
242724252126147Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
6136133647Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
421119Serine or threonine nucleophile; N-terminal nucleophile
354015421234178Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
238315144283692951,344Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1830726223106Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
33332317Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
2111117Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
63334221Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
111115Families of peptidases of unknown catalytic mechanism not assigned to clans
1111116
183013171115104
2226
545620