Peptidases • Suillus "subluteus" FC464 v1.0
Annotations/GenomesSuiame1Suiamp1Suibov1Suibr2Suicli1Suicot1Suidec1Suidis1Suifus1Suigr1Suihi1Suilak1Suilu4Suiocc1Suipal1Suipic1Suipla1Suisu1Suisub1Suisubl1Suitom1Suivar1TotalAnnotation Description
Merops
3423613075123273845983353393714003762872913446712853503163873583198,260
49635160625825467515373673939543543966576055501,721Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
121121112122212111122131Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
15211514172617151616141613131819161917191514365Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
10910712969778976107611812139192Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11111121212418Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11114Water nucleophile; water bound by Gln and Glu; all endopeptidases
222222226232222222322250Families of peptidase inhibitors not assigned to clans
22
11
111121119
23223222222113221222242
222222222222222222222244Families of metallopeptidases not assigned to clans
11121112171713121112121610141113111310141314279Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
121111123211121111121129Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1244516124Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1197810978107101181110912798109200Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
16191416221918171714162015172017151618161622380Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1311151812201516121314171318161614147201314321Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111111111111111111111122Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
6555555785855556555576123Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1111111111111114Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Asparagine nucleophile; all self-processing endopeptidases
1114121212218Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
21202221212223212519222120211922222221242321473Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
53456644465564512555544112Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1013987121091188781011147111014108215Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
101128989491127961051057997122808711912195106931251051032,277Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
311113511213111315161144Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
36454344846103454464663106Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11237Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
111111111111111111111122Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
433334343432343334343372Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
111111112111111211111225
502024218152610323301088621402120321620322951261,011
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