Peptidases • Aspergillus fijiensis CBS 313.89 v1.0
Annotations/GenomesAspcos1Aspfij1Aspfu1Aspibe1Aspjap1Aspni7Aspnid1Aspor1TotalAnnotation Description
Merops
3673532743593513882914142,797
1314416131541392Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
111429Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
771106833678Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
3235503034341034259Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3332433324Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
12111129Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1111116Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile; active peptidase is a homodimer with active site His and Glu from one monomer and Cys from the other. Catalytic residues in the order His, Glu, Cys in each monomer.
6628754341Water nucleophile; water bound by Gln and Glu; all endopeptidases
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
5575555441Families of peptidase inhibitors not assigned to clans
213
11
11
112111310
542574128
11
81513511771480Families of metallopeptidases not assigned to clans
1512131612141625123Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11111128Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
8947785755Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
2426172226264026207Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
141171391781392Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
5434551128Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1111116Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
11Asparagine nucleophile; catalytic residues in the order Asn, Glu in sequence; all self-processing endopeptidases
12137Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2020201821201726162Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
8569484953Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
112Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
11125Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
10118119124974Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1501245914913416061153990Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
76157101744Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
2332431725Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
2252122319Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
111115Serine nucleophile; catalytic residues in the order Ser, Glu, His
1211212111Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
322133923Families of peptidases of unknown catalytic mechanism not assigned to clans
111111118
1111111010981989
11
112
3181338366