Peptidases • Aspergillus brasiliensis v1.0
Annotations/GenomesAspbr1Aspfo1Aspni7Aspnid1Asptu1Batde5Neucr2Pench1Rhior3Sacce1Talma1_2Talst1_2TotalAnnotation Description
Merops
3993723882913733142422952901373463643,811
1612154121031993383824293Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
41218Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
710833105741108103Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
333534103319163328153031317Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
33333332424639Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11211129Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1111111119Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; active peptidase is a homodimer with active site His and Glu from one monomer and Cys from the other. Catalytic residues in the order His, Glu, Cys in each monomer.
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
22Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
56546249849Water nucleophile; water bound by Gln and Glu; all endopeptidases
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
555555351325462Families of peptidase inhibitors not assigned to clans
123
11
11
11
111311332218
444513234737
109771012315358Families of metallopeptidases not assigned to clans
14141416153512101871211178Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1111112111112Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11221119Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
246Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
98858710913510799Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
27252640251114251691315246Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
20161781541011441111131Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
55515644623349Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11111117Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
21911115Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
192020171815232032202125250Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
678495283881078Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11226Serine or threonine nucleophile; N-terminal nucleophile
111112492871831114110Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1681491606115044719253251101291,212Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1041017151071368Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
33313525233336Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
2222211213220Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
12115Serine nucleophile; catalytic residues in the order Ser, Glu, His
11121341421223Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
2233311116Families of peptidases of unknown catalytic mechanism not assigned to clans
1111121111213
101098102413102391113150
11
11
1416
2138131147