Peptidases • Coniophora puteana v1.0
Annotations/GenomesCersu1Conpu1Copci1Cryne_H99_1Hetan2Phchr1Pospl1Pucgr1Schco1SerlaS7_3_2Serla_S7_9Ustma1TotalAnnotation Description
Merops
3404322871573041963621482,226
41591163420818260Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
111012Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
11112118Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
516Water nucleophile; water bound by two Asp
132515141881918130Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
7953764243Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11512111Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
2525Water nucleophile; water bound by Gln and Glu; all endopeptidases
2272222221Families of peptidase inhibitors not assigned to clans
112
11125
325242119
2231342219Families of metallopeptidases not assigned to clans
9173081311157110Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
21115Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11111117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11114Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
9778948456Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
13222213133156107Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
111781014817489Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111115Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
1113Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
6675515540Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11125Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
171819172282018139Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
61083434139Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
213Serine or threonine nucleophile; N-terminal nucleophile
24198119109292Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1361349940967510150731Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
252254323Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3523363126Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
11111117Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
343354527Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
11111117
213210101611206126
112
2125