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Peptidases • Schizosaccharomyces pombe
Annotations/GenomesAscru1Canca1Cybja1Lipst1_1Nadfu1Picme2Saico1Schpo1Wican1TotalAnnotation Description
Merops
1551481672001591342151321821,492
1041410661221276Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
121117114Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
141616221613261718158Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
91223232428Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11122119Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
1111116Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
112Water nucleophile; water bound by Gln and Glu; all endopeptidases
42435253432Families of peptidase inhibitors not assigned to clans
11
112
1211117
22332211420
1112121110Families of metallopeptidases not assigned to clans
9961076107670Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
111112119Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
12125131117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
213Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
68777866661Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
8131910151113419112Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
53754765648Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
34544533334Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
1113Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
192018192019221919175Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
2343358331Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11114Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
76564312438Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
312932602424522344319Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
13127Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
43334343330Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11125Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
32355244432Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1111111119
810913148151410101
112
123
22
111216