Peptidases • Kretzschmaria deusta CBS 826.72 v1.0
Annotations/GenomesAntav1Bisnum1DalEC12_1Entma1HypEC38_3KdCBS826_1Xylhyp1TotalAnnotation Description
Merops
4483443553583753543892,623
21181518161919126Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
112Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
364243325Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
28172223222322157Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
354343426Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
221211110Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11112118Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11114Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
335243323Water nucleophile; water bound by Gln and Glu; all endopeptidases
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
644444531Families of peptidase inhibitors not assigned to clans
11
222212112
436364531
1264443538Families of metallopeptidases not assigned to clans
20191718171815124Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
545555534Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
212112110Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
998108101064Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
26252323252324169Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
13171816171315109Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
333343524Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11111117Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
11125Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
23232423212122157Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
634663533Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1113Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
211212211Serine or threonine nucleophile; N-terminal nucleophile
24212216222217144Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
178112119122140124150945Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
15681210111678Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
344433324Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
211212211Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
111115Serine nucleophile; catalytic residues in the order Ser, Glu, His
433343424Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
3112119Families of peptidases of unknown catalytic mechanism not assigned to clans
21111118
16141418131414103
11
343353425