Peptidases • Cryptococcus terricola JCM 24523 v1.0
Annotations/GenomesCrycu1Cryne_H99_1Cryte1Cryvi1Diocr1Treme1Trich1Triol1TotalAnnotation Description
Merops
2161572311712831492032151,625
17686105131479Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11114Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
3114211316Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1414211533141215138Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
4332745432Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
12121119Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
122117Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11Water nucleophile; water bound by Gln and Glu; all endopeptidases
2232422219Families of peptidase inhibitors not assigned to clans
112
11
3211413318
1121222112Families of metallopeptidases not assigned to clans
9871817911988Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
111211119Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11211118Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
2125Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
88871289868Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
12131212109121292Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
151015815101515103Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111115Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
5555755542Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
1113Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2217202032202122174Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
3333534327Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
1122211111Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
5440833673315155423Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1110216171158Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3333433325Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
111111118Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
3332442425Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
111111118
14101012159131396
11