Peptidases • Paxillus adelphus Ve08.2h10 v2.0
Annotations/GenomesBoled1Gyrli1Hydpi2Paxam1Paxin1Paxru1Paxru2TotalAnnotation Description
Merops
5054213933716062722,568
61180414610438470Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
12122210Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
20131810131286Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
107764438Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
4121311Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
54111158Water nucleophile; water bound by Gln and Glu; all endopeptidases
115537233Families of peptidase inhibitors not assigned to clans
11
11
11
22322213
22122211Families of metallopeptidases not assigned to clans
241411242712112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
212128Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1188811854Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
161617182118106Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1411131013970Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1111116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
22116Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
55557532Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
111115Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
111511423Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
191922202121122Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
54433322Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Serine or threonine nucleophile; N-terminal nucleophile
12891012657Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
90761029011871547Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
631111Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
43533321Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1111116Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
43231215Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1111116
121341029321338601
1113