Peptidases • Pseudovirgaria hyperparasitica CBS 121739 v1.0
Annotations/GenomesCucbe1Dotsy1Melsp1Photr1Psehy1Settu1Symko1TotalAnnotation Description
Merops
3283024883413053243072,395
16102315101612102Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
83612691054Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
28272225222231177Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
435524326Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1111138Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
211231212Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1113Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11111117Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
237233121Water nucleophile; water bound by Gln and Glu; all endopeptidases
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
464545533Families of peptidase inhibitors not assigned to clans
11
123
12111118
346624328
11
457515431Families of metallopeptidases not assigned to clans
1717221522129114Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
754737134Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
112121210Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
6710686649Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
24233025142221159Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
8520911132490Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
333333321Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
21135315Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
23202420192124151Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
878839447Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11114Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
112116Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
91032131215596Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
11710519311811411495856Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
688982647Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
234323320Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
222122314Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
123Serine nucleophile; catalytic residues in the order Ser, Glu, His
543534327Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
11114
1011181111121285
12126
17122316